Nifedipine/Atenolol is a combination drug used for the treatment of hypertension and angina. The active ingredient nifedipine is a calcium channel inhibitor. It works by blocking the calcium channels that are present in cardiac muscles and blood vessels. By reducing the influx of calcium into the cardiac muscles and blood vessels, it causes a decrease in heart rate and also dilates the blood vessels so that blood flow to the heart is increased. This way, it helps improve the functioning of the heart and also decreases blood pressure. The chemical name of nifedipine is dimethyl 2, 6-dimethyl-4-(2-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate and its empirical formula is C17H18N2O6. It has a molecular weight of 346.3346. Atenolol is a beta blocker. It blocks the beta receptors on the heart muscles and blood vessels. When stress hormones like adrenaline or norepinephrine bind to these receptors, it causes heart rate, force of heart beats and blood pressure to increase. It also results in constriction of blood vessels. By binding to these receptors and blocking them, the beta blockers reverse the effects of the hormones and causes vasodilation. This in turn improves cardiac output and reduces blood pressure. Atenolol has the chemical name (RS)-2-{4-[2-hydroxy-3-(propan-2-ylamino) propoxy] phenyl} acetamide. Its molecular formula is C14H22N2O3 and it has a molecular weight of 266.336 g/mol. The combination drug should be taken as prescribed by the doctor. There may be some mild side effects like headache, nausea, dizziness, swollen ankles, flushing but they usually disappear within a few weeks as the body adjusts to the medication.
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